Extreme Uric Acid In Blood May Reduce 11-Year Lifespan: Study
High levels of serum uric acid in the blood could reduce people’s chances of survival and shorten their lifespan for up to 11 years, the researchers say.
The study, published in the journal BMJ Global Health, found evidence of substantial reductions in patient survival associated with extreme serum uric acid (SUA) concentrations in both men and women.
“This is the first study to provide detailed survival statistics for SUA concentrations in Irish men and women in the healthcare system,” said Leonard Browne, lead author of the study, from the University. of Limerick in the United States.
“Our key question was whether SUA, a routinely measured blood marker, could help us predict a patient’s lifespan, other things being equal,” Browne added.
To answer this, the research team collected data from 26,525 patients.
For the men, the message was pretty clear. Median survival was reduced by an average of 9.5 years for men with low levels of SUA and 11.7 years for men with high levels of SUA.
Likewise, for women, it was found that median survival was reduced by almost six years for those with higher SUA levels.
According to the researchers, there was good evidence that high levels of SUA are associated with a range of serious chronic medical conditions such as kidney failure, hypertension, heart disease, stroke, and diabetes.
These known associations may partly explain the high mortality observed in patients with high levels of SUA in the study.
“Indeed, when we examined the cause of death of these patients, we found on the one hand that men and women with very high SUA levels died from cardiovascular causes,” wrote the authors of the study.
“We also found that very low levels of SUA were also associated with a higher risk of death mainly in men. This would of course suggest that very low levels of SUA are also detrimental to survival,” they added. .
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